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To that end, Wayne has designed structures, conducted and funded the development and dissemination of research, developed policy and programs, produced symposia and created networks of like-minded, trans-disciplinary professionals to work together toward the common goal of enhancing the health and well-being of all people.

Wayne founded the annual Symposium on Healthcare Design and the non-profit Center for Health Design in 1986. As the founder, president and CEO, he was responsible for producing 12 Symposia, as well as publishing 10 journals of their proceedings, five significant research projects, and 24 newsletters. He also started three design competitions and developed three built demonstration projects. During this time, he was also the leader of two international study tours and developed graduate healthcare design programs in two universities.

In 1998, Wayne was awarded the highly competitive Loeb Fellowship in Advanced Environmental Studies within the Graduate School of Design at Harvard University. In 1999, he received the distinction of becoming a Visiting Scholar at the American Academy in Rome.